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A significant obstacle is the fierce rivalry between the companies contending for these few spots. To ensure that their IND submissions meet all regulatory requirements & make a lasting impression among the many applicants, companies need to devote a significant amount of time and resources to their preparation. **Competition's Effect on Research Teams**. If research teams are not managed carefully, this competitive environment may result in rushed or subpar submissions & increased pressure. Conversely, the industry's creative spirit and teamwork are stimulated by this competitive environment. To increase their chances of getting an IND slot, businesses might look to form alliances or partnerships with other companies or academic institutions. **Industrial Innovation & Collaboration**.